Right now, not much is known except the following:
Experience the epic sequel to the 2009 Game of the Year from the critically acclaimed makers of Dragon Age: Origins and Mass Effect 2. You are one of the few who escaped the destruction of your home. Now, forced to fight for survival in an ever-changing world, you must gather the deadliest of allies, amass fame and fortune, and seal your place in history. This is the story of how the world changed forever. The legend of your Rise to Power begins now.
* Embark upon an all-new adventure that takes place across an entire decade and shapes itself around every decision you make.
* Determine your rise to power from a destitute refugee to the revered champion of the land.
* Think like a general and fight like a Spartan with dynamic new combat mechanics that put you right in the heart of battle whether you are a mage, rogue, or warrior.
* Go deeper into the world of Dragon Age with an entirely new cinematic experience that grabs hold of you from the beginning and never lets go.
* Discover a whole realm rendered in stunning detail with updated graphics and a new visual style.
So from what I've gathered, they're not heading the way Mass Effect 2 did. Say goodbye to your Grey Warden and say hello to a new character. Ferelden is also possibly out and you'll be exploring a bigger world with new combat techniques and new graphics.
Looks like my paycheck will go to a new video card >.>
Also what HAS been confirmed is that your main character is HUMAN and is called Hawke. There will be Elves and Dwarves, but the main character is only human.
A couple of concept art are available for your viewing pleasure:
You'll notice the last two ones say gameinformer. The lucky bastards got a sneak preview and have their 10-page cover story in issue 208. So go get that issue if you find it. i know i'll be on the look out
When you look at that image (and according to Chris Priestly the box art can still change), the tip of the dragon's wings form people. Could they be the shadows of your companions?
Rumours say that she is Morrigan's daughter and the Warden's.